QUOTE(renatuska23 @ 2015 04 22, 22:57)
Buk gera papasakok man apie ta E2 ?
Tai yra vienas is triju pagrindiniu parametru stimuliacijos eigai vertinti. Neturejau bedu su estradiolio kiekio nukrypimais lyginant su foliuku skaicium irdydziais. Gal kitos mergaites tau pakomentuos issamiau apie tai. Bedrais bruozais tai yra:
Estradiol Levels During In-Vitro Fertilization
Just like Goldilocks' porridge, the estradiol level during an IVF cycle needs to be just right. Too high, you're at risk for hyperstimulation. Too low, your response to your doctor's protocol may not be optimal. But what exactly is a good, low, or high estradiol level? How can you judge the progress of an in-vitro fertilization cycle by the estradiol levels?
It's difficult to give exact numbers because every cycle and body is different, but, in general, a 'good' estradiol level is between 150- 500 pg/ml on day eight of an IVF cycle. Approximate doubling of the day eight value every 48 hours is a positive sign of continued follicle development.
High Estradiol Levels
As for high estradiol levels, anything over 3000 is considered high and at risk for hyperstimulation (also referred to as Ovarian Hyperstimulation Syndrome or OHSS). Because hyperstimulation can be serious, yourfertility treatment center may reduce the dosage on your medications and 'coast' until the levels come down. If levels remain high, the cycle could be canceled due to the risk to your health as well as the fact that coasting for too long can reduce egg quality.
Low Estradiol Levels
Low estradiol levels aren't necessarily better. According to a 2004 study published in the Journal of Assisted Reproduction and Genetics, levels lower than 75 pg/ml were predictive of cycle cancellation.
What to Do When Estradiol Levels Are Too High or Too Low
What can you do as a patient? Know your estradiol level and your clinic's cutoffs for high and low levels. If your estradiol appears to be low or high, ask your doctor to reevaluate your protocol and consider coasting to see if estradiol levels even out. Be sure to discuss the benefits and risks of moving forward as well, especially with regards to Ovarian Hyperstimulation Syndrome and the risk of pregnancy multiples.
