merginos, va zadeta informacija apie T, M, N ir dar daugiau. Cai Amerikos klasifikavimas, bet Europoje irgi, regis, nuo 2004 m. , taikoma ta pati klasifikacija.
sekmes, neliudekite, viskas po truputi susitvarkys, kantrybes tik reikia.
Meginos, as isvaziuoju trejetai savaiciu, tai stengsiuos jus skaityti, tik nezinau, ar galesiu prisijungti. Iki ir linkiu visoms gero pavasario - pats laikas kaupti jegas.
Stage Information
The American Joint Committee on Cancer (AJCC) has designated staging by TNM classification. [1]
TNM Definitions
Primary tumor (T)
All categories may be subdivided into (a) solitary tumor or (

multifocal tumor (the largest determines the classification).
TX: Primary tumor cannot be assessed
T0: No evidence of primary tumor
T1: Tumor 2 cm or less in greatest dimension, limited to the thyroid
T2: Tumor larger than 2 cm but 4 cm or smaller in greatest dimension, limited to the thyroid
T3: Tumor larger than 4 cm in greatest dimension limited to the thyroid or any tumor with minimal extrathyroid extension (e.g., extension to sternothyroid muscle or perithyroid soft tissues)
T4a: Tumor of any size extending beyond the thyroid capsule to invade subcutaneous soft tissues, larynx, trachea, esophagus, or recurrent laryngeal nerve
T4b: Tumor invades prevertebral fascia or encases carotid artery or mediastinal vessels
All anaplastic carcinomas are considered T4 tumors.
T4a: Intrathyroidal anaplastic carcinomasurgically resectable
T4b: Extrathyroidal anaplastic carcinomasurgically unresectable
Regional lymph nodes (N)
Regional lymph nodes are the central compartment, lateral cervical, and upper mediastinal lymph nodes.
NX: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1: Regional lymph node metastasis
N1a: Metastasis to level VI (pretracheal, paratracheal, and prelaryngeal/Delphian lymph nodes)
N1b: Metastasis to unilateral or bilateral cervical or superior mediastinal lymph nodes
Distant metastases (M)
MX: Distant metastasis cannot be assessed
M0: No distant metastasis
M1: Distant metastasis
AJCC Stage Groupings
Separate stage groupings are recommended for papillary or follicular, medullary, and anaplastic (undifferentiated) carcinoma.
Papillary or follicular thyroid cancer
Younger than 45 years
Stage I
Any T, any N, M0
Stage II
Any T, any N, M1
Age 45 years and older
Stage I
T1, N0, M0
Stage II
T2, N0, M0
Stage III
T3, N0, M0
T1, N1a, M0
T2, N1a, M0
T3, N1a, M0
Stage IVA
T4a, N0, M0
T4a, N1a, M0
T1, N1b, M0
T2, N1b, M0
T3, N1b, M0
T4a, N1b, M0
Stage IVB
T4b, any N, M0
Stage IVC
Any T, any N, M1
Medullary thyroid cancer
Stage I
T1, N0, M0
Stage II
T2, N0, M0
Stage III
T3, N0, M0
T1, N1a, M0
T2, N1a, M0
T3, N1a, M0
Stage IVA
T4a, N0, M0
T4a, N1a, M0
T1, N1b, M0
T2, N1b, M0
T3, N1b, M0
T4a, N1b, M0
Stage IVB
T4b, any N, M0
Stage IVC
Any T, any N, M1
Anaplastic thyroid cancer
All anaplastic carcinomas are considered stage IV.
Stage IVA
T4a, any N, M0
Stage IVB
T4b, any N, M0
Stage IVC
Any T, any N, M1