RositaK,tiksliai negaliu pasakyt,bet kiek pamenu is senu skaitalu tai tas lygis pakiles kai truksta b grupes vitaminu-dazniausiai b12 ir folio rugsties.Pas mane pacia b12 del kazkokiu priezasciu daznai per zemas,uztat man rekomenduoja 5mg folio plius pastoviai gert b12.Nezinau kaip LT,bet UK kai kuriose klinikose prie ivf,iui ar siaip stimuliaciju ijungia dar ir b grupes vitaminu,tikriausiai apsisaugot nuo per didelio to homocisteino lygio.Kituose organizmuose naturaliai nesigamina folis,ar jam antikuniai buna.UK viena mergina persileido 19 kartu,kol atseke ,kad ji is vis folio neturi.Tik pradejus ji gerti pagimde graziai mergyte,atrodo gydymas paprastas,o kol atrado kas kur kaip ir kada turejo daug praradimu.
Veliau truputi pasiziuresiu,zinau,kazkur lyg turejau atsiprintinus info apie tuos trukumus.Parasysiu
Va cia truputi info is neto.Raso apie metformino itaka zemiem b vitaminu lygiams,bet esme ta pati,per mazin b kiek kelia ta homocysteine ir problemos tos pacios ar su metforminu ar be.Zinau,kad yra kazkokie antikuniai pries b12,mane tyre,bet nepasitvirtino.Arba gali buti,kad virskinimo sistema neabsorbuoja jo.
ELEVATED HOMOCYSTEINE. People who take Glucophage tend to have higher homocysteine levels.(14) Women with PCOS also tend to have elevated homocysteine.(15)
Homocysteine is an amino acid in the blood. A normal amount is OK. But an elevated level means that your metabolic processes are not working properly. Elevated homocysteine is associated with coronary artery disease, heart attack, chronic fatigue, fibromyalgia,(16) cognitive impairment.(17), and cervical cancer. (18)
Vitamin B12, along with vitamin B6 and folic acid (another B vitamin), is responsible for metabolizing homocysteine into less potentially harmful substances (19). Therefore, when metformin reduces absorption of vitamin B12, you lose one of the nutrients needed to reduce homocysteine and thus reduce your risk of cardiovascular disease.
ELEVATED HOMOCYSTEINE & PREGNANCY COMPLICATIONS. Pre-eclampsia is a complication of pregnancy characterized by increasing blood pressure and edema. If left untreated, pre-ecampsia can lead to eclampsia, a serious condition that puts you and your baby at risk. In a study conducted at the Center for Perinatal Studies at Swedish Medical Center in Seattle, a second trimester elevation of homocysteine was associated with a 3.2 fold increased risk of pre-eclampsia.(20)
The Dept. of Obstetrics and Gynecology, Nijmegen, The Netherlands, reviewed a series of studies on the linkage between elevated homocysteine and early pregnancy loss. They concluded that high homocysteine levels are a risk factor for recurrent early pregnancy loss.(21)
Ovarian follicular fluid contains detectable amounts of homocysteine along with B12, B6, and folic acid. The follicular fluid provides nourishment to the egg by facilitating transport of nutrients from blood plasma. High levels of homocysteine as well as an insufficiency of B vitamins may adversely influence the process of fertilization and early fetal development.(22)
NOTE: We are suggesting that elevated homocysteine, not metformin itself, could contribute to pregnancy complications in some women. However, metformin does contribute to increased homocysteine levels.
PREGNANCY WARNING. Many women use metformin in their pursuit of a successful pregnancy. However, Glucophage is a category B drug, meaning its safety for use while pregnant has not been established. It is found in breast milk so it's not advisable to breast feed while taking Glucophage.
ANEMIA. By preventing optimal absorption of vitamins B12 and folic acid, metformin could induce or contribute to megaloblastic anemia.(23) Megaloblastic anemia occurs when your bone marrow doesn't have enough B vitamins to manufacture red blood cells. Your bone marrow then releases immature and dysfunctional red blood cells into circulation.
Although anemia is not common among people taking metformin, it remains a risk for those whose B12 and folic acid levels were already low when metformin therapy was started.
.Tikrino limfmazgius (pazastyse, kakle,kirksnyse). Po to labai atdižiai gerklę patikrino.Nu tokia šaltoka gydytoja, bet savo srities tikra profesionalė, jai jau pakliūsi pas ja su problemomis taip lengvai nepaleis-gydis iki galo.Be siuntimo pas ja kainuoja 80lt konsultacija. Su siuntimu-nieko. Tyrimai ar su siuntimu ar be yra mokami (vieną kartą mokėjau 20Lt, kitą kartą 80lt). Čia priklausomai kokius daro. Kai mokėjau 80-tai darė-citomegalą;herpes;kaskokį kraujo ištitravimą (leukogramą lygtai).
